Human Sera
Cayman Chemical HydroxytacrInmaleate 100mg
An inhibitor of steroid 5a-reductase types I and II (Kis 6 and 7 nM respectively) a time-dependent inhibitor with apparent Ki values of 17 and 4.3 nM at 10- and 30-minute reaction times respectively decreases prostate weight in a rat model of benign prostatic hypertrophy induced by testosterone at 0.045 and 0.756 mg/kg administered as a solution or in subcutaneous microspheres respectively daily for 28 days also decreases prostate weight in a transgenic model of prostate cancer
Cayman Chemical ThIodIgalactosIde 100mg
A synthetic heptapeptide that acts as a specific substrate for PKA
Cayman Chemical R-Lnsoprazole 50mg
A cell permeable phenoxazine derivative that suppresses IGF-1-stimulated phosphorylation of Akt with an IC50 value of 1-2 M inhibits the growth of Rh1 Rh18 and Rh30 cells with IC50 values of 2-5 M
Cayman Chemical BambuterolhydrochlorIde 100mg
A typical antipsychotic an antagonist of dopamine D2 D3 and D4 receptors (Kis 0.66 0.84 and 1.2 nM respectively) as well as 5-HT2A receptors (Ki 1.8 nM) an antagonist of histamine H1 a1a- a2b- and a2C-adrenergic and M3 muscarinic acetylcholine receptors (Kis 6 0.28 27 46 and 47 nM respectively) increases latency to find the platform in a repealed acquisition water maze task and decreases vertical activity and stereotypic movements in the open field test in rats at 10 mg/kg reduces cisplatin-induced emesis in dogs at 0.3 1 and 3 mg/kg
Cayman Chemical TrIamcInolon acetonIde 100mg
An orally active direct inhibitor of Factor Xa (Ki 0.4 nM) that inhibits thrombin formation without prolonging bleeding time approved for clinical use as an anticoagulant in the prevention of stroke and the treatment of venous thromboembolisms
Cayman Chemical DIgItoxIgenIn 50mg
Immunogen Synthetic peptide from the C-terminal region of human MBOAT5 Host Rabbit Species Reactivity ( ) Human Applications FC and IF
Cayman Chemical DIhydrodaIdzeIn 50mg
A reversible inhibitor of both Aurora A and B kinases (IC50s 0.8 and 5 nM respectively) also inhibits FLT1 FAK TrkA Met and FGFR1 (IC50s 10 22 30 100 and 100 nM respectively)
Cayman Chemical tnofovIr DIsoproxIlfumart 50mg
A sulfhydryl-reactive biotinylation reagent that forms a reversible disulfide linkage used to label protein cysteines and other substrates that contain sulfhydryl groups easily linked with target substrates at pH 6.5 to 7.5 in buffers such as PBS disulfide linkage can be cleaved by reducing agents
Cayman Chemical 7 8-DIhydroxyflavon 100mg
A nucleoside analog with antiviral activity inhibiting thymidine kinases from herpes simplex virus types 1 and 2 with Ki values of 0.14 and 0.95 UM while blocking green monkey Vero cell thymidine kinase less effectively (Ki 53 UM)
Cayman Chemical NnonoylLHomoserIn lacto 50mg
A selective nonpeptide AT2R antagonist (IC50 5.6 nM vs. 100 nM for AT1R) that has been used to selectively examine the specific roles for AT1R and AT2R in hypertensive and other vascular research-related models
Cayman Chemical 1Methyl4ImIdazoleACtIc Ac 50mg
A potential metabolite produced during metabolism of AB-CHMINACA in the liver intended for forensic and research applications
Cayman Chemical BarIcItInIb 50mg
A natural phenol which inhibits the monocarboxylate transporters MCT1 and MCT2 (IC50 28 and 14 UM respectively) also blocks the sodium/D-glucose cotransporter (Ki 86 UM) and the human concentrative nucleoside transporter 3 (Ki 32 UM)
Cayman Chemical GBR 12935hydrochlorIde 100mg
Antigen human recombinant sPLA2 (type IIA) Host mouse Cross-Reactivity ( ) human sPLA2 (type IIA) (−) bee venom sPLA2 (type III) and human sPLA2 (type V) Application(s) IP and WB other applications not tested Isotype IgG1 Clone designation SCACC353
Cayman Chemical ZoledronIc AcIdhydrate 50mg
A stable analog of LTC4 that does not readily metabolize to LTD4 and LTE4 at the expense of marginally reduced biological activity
